K. Alok Pathak, MS, MHM, PhD, FRCSC

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K. Alok Pathak, MS, MHM, PhD, FRCSC

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Research Discipline(s): Translational, Clinical, Health Services

Primary Title: Professor of Surgery (Surgical Oncology), University of Manitoba

Additional Titles & Affiliations: Program Director, Head and Neck Surgical Oncology Fellowship Program, Affiliate scientist, CancerCare Manitoba Research Institute

RESEARCH TOPICS

Head and Neck Cancers, Thyroid Cancers, Salivary Gland Neoplasm, Melanoma

My research mission is to use data generated by research and cutting edge technology like 3D printing and artificial intelligence to promote minimally invasive/ function preserving surgery.

Research Summary

My research has focused on the cancers of head and neck, particularly those of the thyroid and the oral cavity. My research interests span both clinical outcome and translational research. My paper on prognostic nomogram is an important milestone in this endeavor. I have over 140 peer reviewed papers and abstracts, 10 book chapters and edited two volumes of Head and Neck Cancer Clinics. secured. I have two US patents granted and secured over $2 million in grants to support research and infrastructure.

Goals

My research goal is to improve treatment outcomes of head and neck cancer patients through clinical and translational research.

Research Biography

Dr. Pathak completed PhD (human anatomy and cell sciences) from University of Manitoba and Master of Health Management, McMaster University. He completed his medical training and general surgical residency at the Banaras Hindu University in India (MBBS 1991, MS-1994). He is a diplomat of the National Board (1995) and a member of National Academy of Medical Sciences, India (2006). He has mentored numerous graduate and undergraduate students, residents and fellows.

Achievements

  • Surgical Educator of the Year, University of Manitoba (2017)
  • Prix d’ excellence Specialist of the Year-Region 2, Royal College of Surgeons and Physician of Canada (2015)
  • Best Paper award (co-author), Indian Association for Cancer Research annual meeting (2005)
  • UICC-ICRETT fellowship, Netherlands Cancer Institute, Amsterdam (2004)
  • Detroit Fellowship, Indian Association of Surgical Oncology, Wayne State University, Detroit, MI (2004)
  • Honorable mention, IARC International Course on Cancer Epidemiology, Trivandrum, India (2003)
  • UICC-Norwegian Cancer Society Fellowship and Lotus Travel Grant to attend UICC-International Cancer Congress at Oslo, Norway (2002)
  • Best Paper Award by Indian Association of Surgical Oncology in 2002
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    Featured Publications

    • Pathak KA, Goertzen AL, Nason RW, Klonisch T, Leslie WD. A prospective cohort study to assess the role of FDG-PET in differentiating benign and malignant follicular neoplasms. Ann Med Surg (Lond). 2016 Oct 31;12:27-31. doi: 10.1016/j.amsu.2016.10.008. PMID: 27872746; PMCID: PMC5109254.
    • Pathak KA, Wong AK. Followership: The Missing Link in Surgical Leadership. Ann Surg. 2022 Jun 1;275(6):e740-e742. doi: 10.1097/SLA.0000000000005376. Epub 2022 Feb 17. PMID: 35185129.
    • Upreti D, Zhang ML, Bykova E, Kung SK, Pathak KA. Change in CD3ζ-chain expression is an independent predictor of disease status in head and neck cancer patients. Int J Cancer. 2016 Jul 1;139(1):122-9. doi: 10.1002/ijc.30046. Epub 2016 Mar 8. PMID: 26888626
    • Hendrickson-Rebizant J, Sigvaldason H, Nason RW, Pathak KA. Identifying the most appropriate age threshold for TNM stage grouping of well-differentiated thyroid cancer. Eur J Surg Oncol. 2015 Aug;41(8):1028-32. doi: 10.1016/j.ejso.2015.04.014. Epub 2015 May 7. PMID: 25986855.
    • Pathak KA, Leslie WD, Klonisch TC, Nason RW. The changing face of thyroid cancer in a population-based cohort. Cancer Med. 2013 Aug;2(4):537-44. doi: 10.1002/cam4.103. Epub 2013 Jun 26. PMID: 24156026; PMCID: PMC3799288.
    • Pathak KA, Mazurat A, Lambert P, Klonisch T, Nason RW. Prognostic nomograms to predict oncological outcome of thyroid cancers. J Clin Endocrinol Metab. 2013 Dec;98(12):4768-75. doi: 10.1210/jc.2013-2318. Epub 2013 Oct 23. PMID: 24152685.
    • Nason RW, Binahmed A, Pathak KA, Abdoh AA, Sándor GK. What is the adequate margin of surgical resection in oral cancer? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 May;107(5):625-9. doi: 10.1016/j.tripleo.2008.11.013. Epub 2009 Jan 25. PMID: 19168372.
    • Pathak KA, Bhalavat RL, Mistry RC, Deshpande MS, Bhalla V, Desai SB, Malpani BL. Upfront submandibular salivary gland transfer in pharyngeal cancers. Oral Oncol. 2004 Oct;40(9):960-3. doi: 10.1016/j.oraloncology.2004.04.016. PMID: 15380176.

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