Open trials
28
Adult
49
Pediatric
Patients enrolled
68
Adult
177
Pediatric
Trials in pipeline
15
Adult
13
Pediatric
Clinical Trial Unit News
January 22, 2024
National trial evaluates Therapeutic Plasma Exchange in septic shock patients
Septic shock, a life-threatening infection, is among the most common reasons for admission to ICUs in Manitoba and is a leading cause of death. Septic shock leads to uncontrolled inflammation and coagulation abnormalities. Apart from antibiotics and supportive care, there are few treatments available. Cancer patients are at higher risk of infections and septic shock due to immunosuppression from the underlying disease and chemotherapy.
October 23, 2023
Accessible molecular testing contributing to better outcomes for Manitobans
Molecular testing has become more accessible for Manitobans living with cancer after physicians saw its importance in providing patients with the best possible treatment, based on their genetic profile.
September 8, 2023
New cancer drugs hold great promise but often require complex treatment protocols.
The last number of years have seen a proliferation of new innovative cancer drug therapies being tested in clinical trials at CCMB, nationally, and around the world. Some of these therapies have since become available for clinical use while many more are showing promise in current trials.
Benefits for trial sponsors
Under the direction of fifteen disease site groups, the CTU has been the facilitator of clinical trials at CCMB since the late 1960s. Data collected from our participation in national and international research has influenced the standard treatments used today.
With over 50 years of experience partnering with cooperative groups and pharmaceutical companies, we have a proven track record of exemplary trial oversight and administration.
Access to general population within a single care facility
CMB is located in Manitoba’s capital and major city of Winnipeg with 850,000 people (1.4 million provincially). The CTU is integrated within our care facility.
CancerCare Manitoba is the sole provincial cancer authority
All Manitobans diagnosed with cancer are treated through CCMB, most at our Winnipeg centre. We treat patients of all ages, with all cancers and blood disorders.
CancerCare Manitoba is the sole provincial cancer authority
All Manitobans diagnosed with cancer are treated through CCMB, most at our Winnipeg centre. We treat patients of all ages, with all cancers and blood disorders.
Experienced investigators across most cancer types
Owing to our sole provincial cancer authority status, our oncologist investigators have experience across a wide range of cancers and blood disorders.
Strong culture of collaboration
From leadership support to accessing oncologists, the CTU fosters collaboration in a centre large enough for critical mass, and small enough to be relationship-driven.
World-class research governance and oversight
The CTU has well-established trial conduct consistent with national and international standards. We help trial sponsors navigate our site-specific documentation, approvals, and contractual processes.
Service and support throughout the process
We strive to provide effective and efficient trial administration for all stakeholders, ensuring an optimal experience for our patients, sponsors, and investigators
Conducting trials at CCMB
The ideal environment for clinical investigators
Access to patient populations of all demographics and cancer types, leadership commitment, collaboration opportunities, strong partnerships, and the support of funders, policymakers and the larger community make the Clinical Trials Unit at CancerCare Manitoba the perfect environment for oncologists to treat patients and participate in research trials.
The CTU has extensive experience across a spectrum of clinical trial activities, and offers the following services:
- Protocol and consent development
- Case report form design
- Budget and contract negotiation
- Management of ethics documentation, including initial submissions, amendments, and safety reports
- Completion of regulatory documentation
- Screening patients for eligibility
- Obtaining patient consent
- Conducting patient evaluations
- Case report form completion, data management
The CTU Team
Delivering the very best service, support and science.
Led by Led by Jim Slater, the Clinical Trials Unit consists of nearly 50 committed team members, including Research Nurses, Clinical Research Professionals, and Support Staff.
The team is directly involved in providing Manitobans with the opportunity to access novel therapies, allowing patients to gain early access to promising new cancer treatments and furthering our knowledge of cancer and benign hematologic disorders.
The Clinical Trials Unit is organized into four business units
Chief of Research Administration and Operations
Jim Slater
Hematology clinical trials group
Led by Hematologist, Dr. Pamela Skrabek, the hematology clinical trials group is composed of research staff who manage clinical trials for cancers and blood disorders within the lymphoproliferative, hematology, blood and marrow transplant, and leukemia sites within the adult population.
Solid tumour clinical trials group 1
Led by Gynecologic Oncologist, Dr. Alon Altman, the solid tumour clinical trials group 1 is composed of research staff who manage clinical trials for cancers of the genitourinary, thoracic, gynecology and skin disease sites within the adult population.
Solid tumour clinical trials group 2
Led by Medical Oncologist, Dr. Ralph Wong, the solid tumour clinical trials group 2 is composed of research staff who manage clinical trials for cancers of the gastrointestinal, liver, breast, sarcoma, brain, head and neck and pain and symptom disease sites within the adult population.
Pediatric clinical trials group
Led by Pediatric Oncologist/Hematologist, Dr. Geoffrey Cuvelier, the pediatric clinical trials group is composed of research staff who manage clinical trials for all cancers within the pediatric population.
Contact us about Clinical Trial Sponsorship
Phone: (204) 787-4156
Email: ctu_web@cancercare.mb.ca
