Research Discipline(s): Health Services,Translational
Primary Title: Affiliate Scientist, CancerCare Manitoba Research Institute
Additional Titles & Affiliations: Medical Oncologist, CancerCare Manitoba; Assistant Professor, University of Manitoba
RESEARCH TOPICS
Lung Cancer, Geriatric Oncology, Frailty, Ageing and Cancer
CancerCare Manitoba
675 McDermot Ave, Office # ON5029
Winnipeg, MB R3E 0V9
Canada
Research Summary
Interested in the use of clinical and administrative databases to examine outcomes, quality, and disparities in care. I am particularly focused on investigating treatment patterns and outcomes for frail and older patients with cancer to identify opportunities for system improvement and biomarkers to improve understanding of the biology of frailty in patients with cancer.
Goals
Through my research, I hope to better understand factors influencing treatment of older adults with cancer and ultimately improve their experience and outcomes. I also aim to identify biomarkers to help understand the biology of frailty in patients with cancer.
Research Biography
Dr. Dawe is an assistant professor at the University of Manitoba, a medical oncologist at CancerCare Manitoba, and an affiliate scientist with the CancerCare Manitoba Research Institute.
His research focuses on patterns of cancer treatment for older adults with cancer and for patients with lung cancer. He also focuses on the role of frailty in cancer treatment decisions and biomarkers to help understand the underlying biology of frailty in patients with cancer.
His research is funded through grants from the CancerCare Manitoba Foundation, Canadian Institutes of Health Research, and AstraZeneca.
Achievements
- Nominated for two Manitoba Medical Students’ Association Teaching Awards (2020)
- MMSF John Henson Clinical Research Professorship in Population Health Award (2018)
- CancerCare Manitoba Department of Medical Oncology and Hematology Research Award (2018)
- CancerCare Manitoba Department of Medical Oncology and Hematology Education Award (2017)
- MMSF / SBRC Richard Hoeschen Memorial Award (2015)
- McMaster Medical Staff Association Outstanding Fellow Award (2013)
- CIHR/CAMO/Rx&D Research Fellowship (2012)
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Featured Publications
- Mathur S, Prince L, Bucher O, Xue L, Banerji S, Dawe DE. The impact of the modified frailty index on clinical outcomes for stage IV non-small cell lung cancer patients receiving chemotherapy. Journal of Geriatric Oncology. 2022; 13(5): 654-661.
- Okoli, GN, Stirling M, Racovitan F, Lam OLT, Reddy VK, Copstein L, Hsu T, Abou-Setta AM, Dawe DE. Integration of geriatric assessment into clinical oncology practice: A scoping review. Current Problems in Cancer. 2021. 45(3), 100699.
- Rittberg R, Zhang H, Lambert P, Kudlovich R, Kim C, Dawe DE. Utility of the Modified Frailty Index in Predicting Toxicity and Cancer Outcomes for Older Adults with Advanced Pancreatic Cancer Receiving First-Line Palliative Chemotherapy. Journal of Geriatric Oncology, 2021; Jan;12(1):112-117.
- Dawe DE, Harlos CH, Juergens RA. Immuno-Oncology – The New Paradigm of Lung Cancer Treatment. Current Oncology, 2020; 27(April 2020): S78-S86.
- Rittberg R, Sutherland J, Huynh E, Green S, Wiens A, Stirling M, Dawe DE. Assessing the learning needs of the multidisciplinary team on geriatric oncology and frailty. Journal of Geriatric Oncology, 2019, 10(5), pp. 829-831.
- Dawe DE, Wickramasinghe L, Pitz MW, Singh H, Torabi M. Geographical variation and factors associated with non-small cell lung cancer in Manitoba. Can Respir J. 2017:7915905.
- Dawe DE, Pond GR, and Ellis PM. Assessment of referral and chemotherapy treatment patterns for elderly non-small cell lung cancer patients. Clin Lung Cancer. 2016 Nov;17(6):563-572.
- Dawe DE, Christiansen D, Swaminath A, Ellis PM, Rothney J, Rabbani R, Abou-Setta AM, Zarychanski R, Mahmud SM. Chemoradiotherapy versus radiotherapy alone in elderly patients with stage III non-small cell lung cancer: a systematic review and meta-analysis. Lung Cancer. 2016 Sep;99:180-5.
